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ORGANIC CHEMISTRY

Synthesis

Synthetic methodologies to generate new
chemical leads and explore associated
pharmacology 


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MEDICINAL CHEMISTRY

Structure-based drug design

Development of IND safety assessment candidates 
that inhibit the transcriptional kinases CDK12/13,
and the autophagy kinase ULK1


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CHEMINFORMATICS

Structure mining

HTS screening support, virtual screening,
property calculation, bioisosteric design
QSAR, molecular databases


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CHEMICAL BIOLOGY

Kinetic target-guided synthesis

Small molecule inhibition of RNA biogenesis and
RNA-protein interactions using fragment-based  
discovery approach termed kinetic TGS


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