Synthetic methodologies to generate newchemical leads and explore associatedpharmacology
Development of IND safety assessment candidates that inhibit the transcriptional kinases CDK12/13,and the autophagy kinase ULK1
HTS screening support, virtual screening,property calculation, bioisosteric designQSAR, molecular databases
Small molecule inhibition of RNA biogenesis andRNA-protein interactions using fragment-based discovery approach termed kinetic TGS